Resources:
posters, brochures, presentations, case studies

Scientific
Posters

Importance of Preanalytical Blood Collection Methods in Determining Measured Levels of Brain-derived Neurotropic Factor (BDNF) in Human Plasma and Serum AAPS National Biotechnology Conference - May 2016

Brochures

Contract Research Services

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Drug Metabolism (DMPK) Assays

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Bioanalysis for Small Molecules

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Bioanalysis for Macromolecules

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Specimen Collection Kits

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Specimen Collection Kit Supplies

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Non-Proprietary Assay List

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Presentations

Internal Standardization in LC/MS/MS Analysis

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In vitro Assays to Support IND Submissions

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Adventures in Metabolite Profiling with an Accurate Mass QTof

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Case
Studies

Optimizing enzymatic digestion to create a stable derivative enabled us to develop an LC/MS/MS method to measure concentrations of a key biomarker directly related to the activity of a biologic.
The development of a novel extraction and derivatization scheme allowed us to simultaneously determine free and covalently bound drug concentrations using a single assay.
Employing selective extraction in method development enabled the accurate determination of in vivo drug concentration in plasma samples collected during our client’s Phase I trial.
Customizing specimen collection kits for specific clinical trial sampling requirements streamlined our client’s Phase I study and helped ensure that all specimens collected were stabilized, properly labeled, and provided accurate pharmacokinetic data.
Increasing assay sensitivity to determine drug concentration in epithelial lining fluid (ELF) samples allowed our client’s clinical trial to proceed uninterrupted, saving them time and resources.