Immunoassay (ELISA)

MicroConstants develops and validates highly sensitive and specific immunoassays for quantifying your peptides or proteins in various types of formulation and biological matrices. We will develop a custom ELISA immunoassay, utilize a commercially available ELISA/EIA kit, or transfer and validate a non-GLP method under GLP regulations. Each assay is optimized to yield the best assay range and performance in order to support your preclinical toxicology and clinical studies.

Additionally, we have experience conducting immunogenicity testing, biomarker assays, and enzymatic activity assays and can perform cell-based assays as well.

Custom ELISA Method Development & Validation

For novel protein therapeutics, MicroConstants offers full-service custom immunoassay development and validation services. Our dedicated Immunology Department will design, develop, and validate custom immunoassays using the antibody of your choice, or of commercial origin. If needed, we can also assist with the generation of custom/novel antibodies against your protein therapeutic. Samples from preclinical and clinical studies can be sent to MicroConstants for PK/TK sample analysis.

ELISA Kit Validation & GLP Method Transfer

In addition to custom ELISA development, we will qualify or validate commercially available ELISA/EIA kits for your preclinical or clinical sample analysis needs. We will identify the best available assay kit and evaluate it for compatibility with your peptide or protein. For assays developed in non-GLP laboratories, we can transfer and validate them at MicroConstants under GLP regulations.