Non-Proprietary Assay List

Throughout the past decade, MicroConstants has developed more than 1,400 methods, including over 100 non-proprietary methods. Below is a list of the non-proprietary assay methods we have developed. For a printable version of this list, please visit our Resources page. If you would like more information about any of these methods, please send us an email to This e-mail address is being protected from spambots. You need JavaScript enabled to view it. or fill out our contact form.

Drug	Species	Matrix	Technique	Anticoagulant	Extraction Volume	Range	Stable Labeled I.S.
2-Deoxy-D-Glucose	Human	Plasma	LC/MS/MS	Heparin	0.1 mL	0.25-50 µg/mL	Yes
2-Deoxy-D-Glucose	Human	Urine	LC/MS/MS	N/A	0.1 mL	1-200 µg/mL	Yes
5-Amino Salicylic acid N-Acetyl-5-ASA	Rabbit	Plasma	HPLC/UV	Sodium Citrate	0.1 mL	50-5,000 ng/mL	No
5-Amino Salicylic acid N-Acetyl-5-ASA	Dog	Plasma	HPLC/UV	Sodium Citrate	0.1 mL	50-5,000 ng/mL	No
5-Amino Salicylic acid N-Acetyl-5-ASA	Rabbit	Plasma	LC/MS/MS	EDTA	0.025 mL	25-10,000 ng/mL 50-20,000 ng/mL	Yes
5-Amino Salicylic acid N-Acetyl-5-ASA	Dog	Plasma	LC/MS/MS	EDTA	0.025 mL	50-25,000 ng/mL 25-12,500 ng/mL	Yes
5-Fluorouracil	Human	Plasma	LC/MS/MS	Heparin	0.05 mL	5-2,500 ng/mL	Yes
Acetaminophen	Human	Plasma	HPLC/UV	Heparin	0.1 mL	0.5-50 µg/mL	No
Alprazolam α-OH-Alprazolam 4-OH-Alprazolam	Human	Plasma	LC/MS/MS	EDTA	0.050 mL	0.100-100 ng/mL	Yes
Amitriptyline Nortriptyline	Human	Plasma	LC/MS/MS	Heparin	0.1 mL	0.25-250 ng/mL	Yes
Anandamide	Human	Plasma	LC/MS/MS	Heparin	0.1 mL	0.1-5 ng/mL	Yes
Anastrozole	Human	Plasma	LC/MS/MS	Heparin	0.1 mL	1-100 ng/mL	Yes
Aplindore	Human	Plasma	LC/MS/MS	Heparin	0.5 mL	10-5,000 pg/mL	Yes
Atorvastatin p-hydroxyatorvastatin o-hydroxyatrovastatin	Human	Plasma	LC/MS/MS	EDTA or Heparin	0.05 mL	0.1-20 ng/mL	Yes
Benzoic acid	Minipig	Plasma	HPLC/UV	EDTA	0.1 mL	50-2,000 ng/mL	No
Benzoylecgonine	Human	Plasma	LC/MS/MS	Heparin	0.2 mL	25-10,000 ng/mL	Yes
Benzyl alcohol	Human	Plasma	HPLC/UV	EDTA	0.1 mL	1-100 µg/mL	No
Bromfenac	Human	Serum	HPLC/UV	N/A	0.25 mL	50-10,000 ng/mL	No
Caffeine 1,7-dimethylxanthine	Human	Plasma	LC/MS/MS	Heparin	0.1 mL	100-50,000 ng/mL 50-25,000 ng/mL	No
Caffeine 1,7-dimethylxanthine	Human	Urine	LC/MS/MS	N/A	0.1 mL	500-25,000 ng/mL	No
Calcipotriene	Human	Plasma	LC/MS/MS	Heparin	1.0 mL	10-2,000 pg/mL	No
Campesterol ß-Sitosterol Campestanol Sitostanol	Human	Plasma	LC/MS/MS	EDTA	0.1 mL	1,000-8,800 ng/mL 1,000-13,400 ng/mL 4-1,000 ng/mL 5-1,700 ng/mL	Yes
Carboxyethyphosphoramide mustard (CEPM)	Human	Plasma	LC/MS/MS	Heparin	0.05 mL	0.05-50 µg/mL	Yes
Cephalothin	Rat	Plasma	HPLC/UV	Heparin	0.1 mL	0.5-50 µg/mL	No
Cetylpyridinium	Human	Plasma	LC/MS/MS	Heparin	0.1 mL	1-200 ng/mL	Yes
Chloroadenine	Human	Plasma	LC/MS/MS	Heparin	0.1 mL	1-500 ng/mL	No
Cimetidine	Human	Plasma	LC/MS/MS	EDTA or Heparin	0.05 mL	5-5,000 ng/mL	Yes
Citrulline	Rat	Plasma	LC/MS/MS	Heparin	0.1 mL	2-200 µg/mL	No
Clindamycin Clindamycin sulfoxide	Human	Plasma	LC/MS/MS	EDTA	0.05 mL	50-20,000 pg/mL	No
Clobetasol propionate	Human	Plasma	LC/MS/MS	EDTA	0.4 mL	20-10,000 pg/mL	No
Clozapine	Human	Plasma	LC/MS/MS	Heparin	0.05 mL	0.2-200 ng/mL	Yes
Cocaine Norcocaine Cocaethylene	Human	Plasma	LC/MS/MS	Heparin	0.2 mL	25-10,000 ng/mL	Yes
Cordycepin	Human	Whole Blood	LC/MS/MS	EDTA	0.05 mL	0.1-10 µg/mL	Yes
Cortisol 6ß-hydroxycortisol	Human	Urine	LC/MS/MS	N/A	1.0 mL	5-250 ng/mL 50-2,500 ng/mL	No
Cytarabine	Human	Plasma	LC/MS/MS	EDTA	0.05 mL	2-500 ng/mL	Yes
Daunorubicin Daunorubicinol	Human	Plasma	LC/MS/MS	EDTA	0.1 mL	1-1,000 ng/mL 0.2-200 ng/mL	Yes
Diclofenac	Human	Plasma	LC/MS/MS	Heparin	0.1 mL	1-1,000 ng/mL	Yes
Digoxin	Human	Plasma	LC/MS/MS	Heparin	0.2 mL	0.1-10 ng/mL	Yes
Docetaxel	Human	Plasma	LC/MS/MS	Heparin	0.25 mL	0.5-100 ng/mL	Yes
Econazole	Human	Plasma	HPLC/UV	Heparin	1.0 mL	20-1,000 ng/mL 20-1,000 ng/mL	No
Econazole	Human	Plasma	LC/MS/MS	EDTA	0.2 mL	100-50,000 pg/mL	No
Erlotinib	Human	Plasma	LC/MS/MS	Heparin	0.025 mL	10-10,000 ng/mL	Yes
Ethinyl estradiol	Human	Plasma	LC/MS/MS	Heparin	0.5 mL	2-500 pg/mL	Yes
Etoposide	Human	Plasma	LC/MS/MS	Heparin	0.02 mL	0.100-100 µg/mL	Yes
Fentanyl	Human	Plasma	LC/MS/MS	Heparin	0.1 mL	50-20,000 pg/mL	No
Fludarabine desphosphate	Human	Plasma	LC/MS/MS	Heparin	0.1 mL	0.5-500 ng/mL	No
Ganaxolone	Human	Plasma	LC/MS/MS	EDTA	0.2 mL	5-1,500 ng/mL	No
Gefitinib	Human	Plasma	LC/MS/MS	Heparin	0.05 mL	5-1,000 ng/mL	Yes
Gentamicin	Human	Plasma	LC/MS/MS	Heparin	0.05 mL	2-5,000 ng/mL	Yes
Gemcitabine	Human	Plasma	LC/MS/MS	Heparin	0.05 mL	10-10,000 ng/mL	Yes
Gemfibrozil	Human	Plasma	LC/MS/MS	Heparin	0.025 mL	0.1-500 µg/mL	Yes
Glimepiride	Human	Plasma	LC/MS/MS	Heparin	0.05 mL	2-2,000 ng/mL	Yes
Glyburide	Human	Plasma	LC/MS/MS	EDTA or Heparin	0.1 mL	1-500 ng/mL	No
Histamine N-methylhistamine	Human	Plasma	LC/MS/MS	EDTA	0.5 mL	0.2-50 ng/mL	Yes
Histamine N-methylhistamine	Human	Urine	LC/MS/MS	N/A	0.05 mL	10-2,000 ng/mL 50-10,000 ng/mL	Yes
Ketoconazole	Human	Plasma	LC/MS/MS	EDTA	0.05 mL	5-5,000 ng/mL	Yes
L-Arginine	Human	Plasma	HPLC/UV	Heparin	0.125 mL	1-250 µg/mL	No
L-Methionine	Human	Plasma	LC/MS/MS	Heparin	0.1 mL	1-200 µg/mL	Yes
Lamotrigine	Human	Plasma	LC/MS/MS	Heparin	0.025 mL	0.025-25 µg/mL	Yes
Levofloxacin	Human	Plasma	LC/MS/MS	Heparin	0.025 mL	10-10,000 ng/mL	Yes
Lidocaine	Human	Plasma	LC/MS/MS	Heparin	0.1 mL	0.2-100 ng/mL	No
Lidocaine	Human	Plasma	LC/MS/MS	EDTA	0.1 mL	0.2-100 ng/mL	Yes
Lidocaine 2,6 - dimethylaniline Monoethylglycinexylidide Glycinexylidide	Human	Plasma	LC/MS/MS	EDTA or Heparin	0.1 mL	0.2-200 ng/mL 1-1,000 ng/mL	Yes
Lucanthone Hycanthone	Human	Plasma	LC/MS/MS	Heparin	0.05 mL	1-200 ng/mL	Yes
Metformin	Human	Plasma	LC/MS/MS	Heparin	0.05 mL	10-2,000 ng/mL	Yes
Methotrexate	Human	Plasma	LC/MS/MS	Heparin	0.05 mL	1-1,000 ng/mL	Yes
Midazolam	Human	Plasma	LC/MS/MS	EDTA	0.1 mL	0.5-250 ng/mL	No
Midazolam 1-hydroxymidazolam	Human	Plasma	LC/MS/MS	EDTA	0.1 mL	0.5-100 ng/mL	Yes
Mifepristone	Human	Plasma	LC/MS/MS	Heparin	0.05 mL	10-2,000 ng/mL	Yes
Mitiglinide	Human	Plasma	LC/MS/MS	Heparin	0.1 mL	1-1,000 ng/mL	No
Mitomycin	Human	Plasma	LC/MS/MS	EDTA	0.05 mL	10-5,000 ng/mL	No
Morphine Morphine-6-ß-D-glucuronide	Human	Plasma	LC/MS/MS	Heparin	0.1 mL	0.5-500 ng/mL	Yes
N-acetylcysteine	Dog	Plasma	LC/MS/MS	EDTA	0.025 mL	1-1,000 µg/mL	Yes
N-acetylcysteine	Rabbit	Plasma	LC/MS/MS	EDTA	0.025 mL	1-1,000 µg/mL	Yes
Nabilone	Human	Plasma	LC/MS/MS	Heparin	0.5 mL	100-20,000 pg/mL	No
Naloxone	Human	Plasma	LC/MS/MS	Heparin	0.25 mL	0.1-50 ng/mL	No
Nalbuphine	Human	Plasma	LC/MS/MS	Heparin	0.25 mL	0.1-50 ng/mL	No
Naproxen	Human	Plasma	LC/MS/MS	Heparin	0.025 mL	0.100-100 µg/mL	Yes
Norethindrone	Human	Plasma	LC/MS/MS	Heparin	0.25 mL	20-10,000 pg/mL	Yes
Norgestrel 17-deacetylnorgestimate	Human	Plasma	LC/MS/MS	Heparin	0.25 mL	40-20,000 pg/mL 20-10,000 pg/mL	Yes
Ondansetron	Human	Plasma	LC/MS/MS	Heparin	0.05 mL	0.5-250 ng/mL	Yes
Oxycodone	Human	Plasma	LC/MS/MS	EDTA or Heparin	0.1 mL	0.2-50 ng/mL	Yes
Oxycodone Oxymorphone Noroxycodone	Human	Plasma	LC/MS/MS	Heparin	0.5 mL	0.05-25 ng/mL	Yes
Paclitaxel	Human	Plasma	LC/MS/MS	EDTA or Heparin	0.1 mL	0.5-200 ng/mL	No
Prilocaine	Human	Plasma	LC/MS/MS	EDTA	0.05 mL	0.2-100 ng/mL	No
Promethazine	Human	Plasma	LC/MS/MS	Heparin	0.1 mL	0.2-100 ng/mL	No
Quetiapine	Human	Plasma	LC/MS/MS	EDTA or Heparin	0.05 mL	1-1,000 ng/mL	Yes
Repaglinide	Human	Plasma	LC/MS/MS	EDTA	0.05 mL	0.1-100 ng/mL	Yes
Riboflavin Riboflavin 5-phosphate	Dog	Plasma	Fluorescence	Heparin	0.05 mL	20-10,000 ng/mL 40-20,000 ng/mL	No
Riboflavin Riboflavin 5-phosphate	Rat	Plasma	Fluorescence	Heparin	0.05 mL	20-10,000 ng/mL 40-20,000 ng/mL	No
Rifampin 25-desacetylrifampin	Human	Plasma	LC/MS/MS	EDTA	0.05 mL	0.1-20 µg/mL	Yes
Riluzole	Human	Serum	LC/MS/MS	N/A	0.1 mL	1-500 ng/mL	No
Risperidone 9- hydroxyrisperidone	Human	Plasma	LC/MS/MS	Heparin	0.05 mL	0.1-100 ng/mL	Yes
Rosuvastatin n-desmethyl rosuvastatin	Human	Plasma	LC/MS/MS	Heparin	0.1 mL	0.1-50 ng/mL	Yes
Simvastatin Simvastatin hydroxy acid	Human	Plasma	LC/MS/MS	Heparin	0.25 mL	0.05-50 ng/mL	Yes
Sorafenib	Human	Plasma	LC/MS/MS	EDTA	0.05 mL	10-10,000 ng/mL	Yes
Sumatriptan	Human	Plasma	LC/MS/MS	Heparin	0.1 mL	1-200 ng/mL	No
Tolbutamide	Human	Plasma	LC/MS/MS	EDTA	0.1 mL	0.1-20 µg/mL	No
Tolbutamide 4-hydroxytolbutamide	Human	Urine	LC/MS/MS	N/A	0.1 mL	0.1-20 µg/mL	No
Trazodone	Human	Plasma	LC/MS/MS	Heparin	0.05 mL	0.2-200 ng/mL	Yes
Tretinoin	Human	Plasma	LC/MS/MS	EDTA	0.2 mL	0.4-10 ng/mL	Yes
Valerenic acid Hydroxyvalerenic acid Acetoxyvalerenic acid	Human	Plasma	LC/MS/MS	Heparin	0.2 mL	1-500 ng/mL	No
Vancomycin	Human	Plasma	LC/MS/MS	Heparin	0.02 mL	50-25,000 ng/mL	No
Warfarin (R-)	Human	Plasma	LC/MS/MS	Heparin	0.025 mL	2-2,000 ng/mL	Yes
Warfarin (S-)	Human	Plasma	LC/MS/MS	Heparin	0.025 mL	2-2,000 ng/mL	Yes
Yohimbine	Human	Plasma	LC/MS/MS	EDTA	0.1 mL	0.1-50 ng/mL	No
Zolpidem	Human	Plasma	LC/MS/MS	EDTA	0.05 mL	1-150 ng/mL	Yes
Zolpidem	Baboon	Plasma	LC/MS/MS	EDTA	0.05 mL	1-1,000 ng/mL	Yes