David F. Beyerlein
David F. Beyerlein has over 20 years of experience managing laboratory operations, is an experienced analytical chemist, and is highly skilled in the use of the mass spectrometer. David co-founded MicroConstants with Gil in 1998. As General Manager, he is responsible for overseeing and managing all laboratory operations, project and sample management, and purchasing. Prior to co-founding MicroConstants, David was part of the mass spectrometry group at Covance’s facility in Madison, Wisconsin. Before joining Covance, he was a Senior Research and Development Scientist the Madison facility of PPD where he started their Bioanalytical LC/MS/MS Department. David received his bachelor’s degree in Chemistry from the University of Wisconsin – Eau Claire.
Jose V. Buenviaje
Vice President, Quality Assurance
Jose V. Buenviaje has over 27 years of research, analytical, and manufacturing experience in the biotechnology industry and more than 25 years of experience with Quality Assurance Compliance related to cGLP and cGMP regulations. As Vice President of Quality Assurance, Jose serves as the executive quality authority in all interactions with Regulatory representatives. He is also responsible for the creation, compliance, and deployment of MicroConstants’ global quality system, including internal GLP policies and procedures consistent with internationally recognized standards. Prior to joining MicroConstants in 1999, Jose was the Quality Assurance Supervisor at Syntron Bioresearch, a licensed Medical Device Establishment in Carlsbad, California. Before Syntron, Jose spent five years working in the field of forensic chemistry and has testified as an expert witness in the field of toxicology for numerous cases for the state of California. Jose received his bachelor’s degree in Biology/Psychology from the University of California, San Diego.
David A. Johnson, Ph.D.
Senior Director, Drug Metabolism
David A. Johnson has over 20 years of experience implementing and managing preclinical drug discovery contract research services. In 2000, he joined MicroConstants, establishing the Drug Metabolism group which is responsible for preclinical drug metabolism research and non-GLP discovery bioanalytical research. Previously, David was the Drug Metabolism Product Development Manager for the Pharmazyme division of Immune Complex Corporation. Prior to Pharmazyme, David was a Research Assistant at Hybritech where he developed methods to automate the radiolabeling of monoclonal antibodies for use in medical diagnostic kits. He received his bachelor’s degree in Chemistry from the University of California, San Diego and his Ph.D. from the University of Minnesota, Twin Cities.
Richard W. Egolf
Director, Business Development
Richard Egolf has over 13 years of business development experience offering contract research services to pharmaceutical, biotech and medical device companies. Since joining MicroConstants in 2014 as Director of Business Development, Richard has been responsible for developing new business opportunities in the United States. Before joining MicroConstants, Richard was a Business Development Manager at Absorption Systems representing all areas of service; DMPK, ocular, biologics and medical device. He received his bachelor’s degree in Microbiology from Pennsylvania State University in University Park, Pennsylvania.
Bruce A. Babson
Director, Method Development
Bruce Babson has over 40 years of experience developing chromatographic methods for regulated analysis. Bruce started his career as a Chemist in his home state of North Carolina. The analytical methods he developed to analyze samples for pesticides, herbicides, other potential soil and air pollutants became the industry standard for both the EPA and USDA. He also supported arson investigations by analyzing accelerants and was recognized as an expert witness in that field. After moving to Madison, Wisconsin, Bruce joined PPD where he managed their bioanalytical R&D Department. Bruce received his bachelor’s degree in Chemistry from the University of North Carolina – Chapel Hill.
John Marcelletti, Ph.D., MBA
Vice President, Large Molecule Bioanalytical Operations
John Marcelletti has over 25 years of drug development experience, much of which involving regulated bioanalytical lab operations (GLP, CLIA, CAP). As Vice President of Large Molecule Bioanalytical Operations, he oversees the development and validation of immunoanalytical and enzymatic methods in support of large molecule drug development, including preclinical and clinical pharmacokinetic, anti-drug antibody, and biomarker analyses. Previously, Dr. Marcelletti was Senior Lab Director of Immunoanalytical & Cell-based Biotechnology Services for Tandem Labs San Diego (LabCorp Clinical Trials). Prior to that, he held a variety of positions directing translational medicine operations in oncology, virology, and autoimmunity, mostly focused on incorporation of biomarkers into clinical studies as PD and CDx tools for drug development. His team at Avanir Pharma was integral in the invention, development, and FDA approval of Abreva®, a topical antiviral therapeutic for recurrent herpes labialis. John received his Ph.D. from the Department of Immunology and Microbiology, Wayne State University School of Medicine, Detroit, Michigan. He also holds an MBA from The Haworth College of Business at Western Michigan University. He has >80 scientific publications including primary research journal articles, book chapters, and patents.
Associate Director, Immunology
Trang Le has more than 20 years of leadership experience in large molecule immunochemistry analyses in a regulated laboratory environment. At MicroConstants, Trang plays a key role in coordinating the activities of the immunology scientific staff, drives development and validation projects for large molecule drug immunoanalytical methods in support of regulated pharmacokinetic (PK), toxicokinetic (TK), and antidrug antibody (ADA) analyses of preclinical and clinical biological samples. Trang joined MicroConstants from BioAgilytix Labs where she was the Principal Scientist developing & validating biomarker, cell-based immunogenicity, immunoassays and enzymatic assays for support of preclinical, clinical and product release studies. From 1999-2015, Trang was the Project Manager/Principal Investigator at Intertek Pharmaceutical Services making sure analytical assays (cell-based, ELISA, & ECL) met the final requirements of QA review and release of data and reports to clients. Prior to those roles, she worked at Performance Bioanalytical Inc., at PharMingen, and at Scripps Immunology Reference Laboratory. Trang received her bachelor’s degree in Biochemistry and Cell Biology from the University of California, San Diego.
Thu Hanesana received her bachelor’s degree in General Biology with a minor in Psychology from University of California, San Diego and has over 16 years of experience in the pharmaceutical industry. She joined MicroConstants in 2019 as Manager of Immunology, where she oversees the day-to-day operations of the Immunology department. She also serves as the Validation Study Director and Principal Investigator for method validation and sample analysis, respectively. Previously, Thu was a Bioanalytical Project Manager at LabConnect, Inc. where she was contracted to a pharmaceutical company to oversee the CROs performing method development, method validation, and sample analysis for the programs that she was assigned to. Thu monitored performance of the methods, provided analytical oversight through data review and trending analysis, managed timelines, and provided troubleshooting support to CROs. Prior to that, she was a Principal Investigator at Intertek Pharmaceutical Services and was employed there for over 14 years. Thu has held other roles at GenomeDx (now Decipher Diagnostics), where she worked on prostate, breast, and bladder cancer research and Dermatrends, Inc., a drug delivery/skin sciences company.
Director, Bioanalytical/Formulation Chemistry
Jeff Hoffman has more than 24 years of experience in the contract research and pharmaceutical industries. He joined MicroConstants in 2004, and currently serves as Director for the Bioanalytical Chemistry and Formulation Analysis departments. In this role, he oversees the day-to-day operations of the Bioanalytical and Formulation departments and offers hands-on leadership in the areas of method validation and analytical sample analysis. Previously, Jeff was at Dermtech/Pracs Institute where his responsibilities included analytical method development, method validation, and supervision of the transdermal laboratory operations. Prior to that, he was an analytical chemist in the Toxicology Department at PoisonLab. Jeff received his bachelor’s degree in Biology and Zoology from Humboldt State University in Arcata, California.
Senior Manager, Bioanalytical Chemistry
Gregory Reynolds has more than 15 years of experience in the contract research and pharmaceuticals industries. Gregory’s current role is to provide guidance and support as a Principal Investigator to a lab of scientists conducting regulated validation, sample analysis and method development. Prior to joining MicroConstants in 2006, Gregory was at Invitrogen where his responsibilities included organic synthesis of transfection reagents, purification by multiple chromatographic techniques and QC/detection by protein expression. Gregory received his bachelor’s degree in General Chemistry from University of California San Diego where his undergraduate research consisted of synthesis and crystallization of transition metal complexes.
Manager, Formulation Chemistry
Jason Conerty joined MicroConstants in 2002 as an Analytical Scientist performing regulated bioanalysis. In 2004, Jason moved to the Formulation department and began developing and validating methods for dose formulation analysis. In 2012, he began performing Certificate of Analysis under GLP guidelines for reference standard certification. Jason is currently Manager of Formulation Chemistry. Jason received his bachelor’s degree in Chemistry from San Diego State University.
Supervisor, Bioanalytical Chemistry
Yazmin Alatorre has more than 5 years of experience in the contract research and pharmaceutical industries. She joined MicroConstants in 2014 and currently serves as a Principal Investigator for the Bioanalytical Chemistry department. Previously, Yazmin was MicroConstants’ Certified Scientific Trainer where her responsibilities included making sure new scientists had the skills and support they needed to be the best in the industry. Yazmin received her bachelor’s degree with a double major in Chemistry and Biological Science from the University of California, Irvine.
Director, Project Operations
Michelle Mason joined MicroConstants in 2002 and that same year was promoted to Project Coordinator. Michelle is now the Director of Project Operations and responsible for overseeing day-to-day project operations, implementing strategies to enhance client services, and identifying opportunities to improve efficiency throughout the company. Michelle also manages the Project Management and Sample Management departments. She earned her bachelor’s degree in Psychology from San Diego State University in California.
Manager, Corporate Operations
Vielka Damond joined MicroConstants in 2008 as a Clinical Kit Coordinator. The following year, she transitioned into the Accounting department and became a Purchasing Agent. Vielka is now the Manager of Corporate Operations and responsible for overseeing day-to-day operations of the Clinical Kits, Purchasing, Housekeeping, and Facilities departments to improve efficiency throughout the company. Vielka earned her degree in Business Management and Accounting from Independence University in Salt Lake City, Utah.