Gyrolab

Fast Assay Results for Nanoliter-Scale Immunoassays

BioAgilytix uses the cutting-edge Gyros platform to perform immunoassays on a nanoliter scale, generating high-quality data from small volumes of precious sample. Gyrolab automates finely controlled immunoassays in identical microfluidic channels using highly sensitive, laser-induced fluorescence (LIF) detection.

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HOW THE GYROLAB PLATFORM WORKS

Gyrolab xP uses proprietary Gyrolab CD technology, which is engineered with highly reproducible nanoliter microfluidics for development of robust, nanoliter-scale immunoassays exhibiting broad dynamic ranges. Within each CD itself, a volume definition chamber delivers ultra-accurate sample volumes, with hydrophobic breaks to ensure consistency in volume delivery. An overflow channel eliminates the need for manual pipetting accuracy, and a 15-nl affinity capture column mitigates non-specific binding.

Once CDs are loaded into the Gyrolab workstation – up to 5 discs in a series – the platform performs parallel sample processing via high-sensitivity, laser-induced fluorescence detection. The CDs are spun at controlled speeds to ensure optimal binding and uniform conditions for all assays. This is possible through a precise, automated control of centrifugal and capillary forces, which steer liquid flow through nanoliter-scale microfluidic structures contained within the CD.

Platform Spotlight: Gyros

Learn more about the capabilities, uses, and benefits of using the Gyros xP Workstation platform to perform immunoassays on a nanoliter scale in this featured blog.