Publications

Interview with David Beyerlein on Multi-site Validation and 8th WRIB

Interview with David Beyerlein on Multi-site Validation and 8th WRIB
Our VP of Global Operations, David Beyerlein, spoke with Bioanalysis Zone regarding multi-site validation to safely remove anthrax spores from study samples as presented in a poster at the 8th annual Workshop on Recent Issues in Bioanalysis (WRIB). View the poster David is discussing in the interview.

C-Ring Cannabinoid Lactones: A Novel Cannabinergic Chemotype

ACS Medicinal Chemistry Letters, January 2014
One of our DMPK scientists, Rishi Sharma, Ph.D., co-authored a paper on C-Ring Cannabinoid Lactones: A Novel Cannabinergic Chemotype which was published in the ACS Medicinal Chemistry Letters. The paper was a result of his graduate research at Northeastern University.
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Maternal Administration of Solithromycin, a New, Potent, Broad-Spectrum Fluoroketolide Antibiotic, Achieves Fetal and Intraamniotic Antimicrobial Protection In a Pregnant Sheep Model

Journal of Antimicrobial Agents and Chemotherapy, November 2013
One of our sponsors, Cempra Pharmaceuticals, successfully demonstrated the ability of their antibiotic, solithromycin, to cross the maternal/fetal barrier in a pregnant sheep model. MicroConstants provided the analytical support for this study and David Johnson, Ph.D., our Director of DMPK, contributed to a paper that was published on the story in the December issue of the Journal of Antimicrobial Agents and Chemotherapy.
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Controlled-Deactivation Cannabinergic Ligands

Journal of Medicinal Chemistry, November 2013
One of our DMPK scientists, Rishi Sharma, Ph.D., co-authored a paper on Controlled-Deactivation Cannabinergic Ligands which was published in the Journal of Medicinal Chemistry. The paper was a result of his graduate research at Northeastern University.
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Ask the Experts: Outsourcing in a Bioanalytical Laboratory

Bioanalysis, October 2013
David Beyerlein, our Vice President of Global Operations, was interviewed for the Ask the Experts: Outsourcing in a Bioanalytical Laboratory article which appeared in the October issue of Bioanalysis. The Journal invited a selection of leading researchers to express their views on outsourcing bioanalysis, including ways to effectively manage costs while maintaining productivity and quality of work. Their responses provide valuable insight into the impact of outsourcing and the future of the constantly evolving bioanalytical laboratory.
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Perspective On: A Contract Research Lab

Lab Manager Magazine, March 2012
David Beyerlein, our Vice President of Global Operations, was interviewed by Lab Manager Magazine for their March issue. Read the article to get our perspective on running a bioanalytical CRO, including our inventory management and maintenance procedures, communication policies, and some of the challenges we have faced.
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One Step Ahead: The Benefits of Being Proactive Versus Reactive in Hiring and Purchasing Practices

Lab Manager Magazine, October 2011
David Beyerlein, our Vice President of Global Operations, was invited to contribute to the October issue of Lab Manager Magazine. Read the article to learn why we have chosen to expand proactively in an effort to reduce risk for our clients, maintain our reputation, and reach our long-term goals.
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Pharmacokinetics in Mice Implanted With Xenografted Tumors After Intravenous Administration of Tasidotin (ILX651) or Its Carboxylate Metabolite

The AAPS Journal, December 2007
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Phase I and Pharmacokinetic Study of Tasidotin Hydrochloride (ILX651), a Third-Generation Dolastatin-15 Analogue, Administered Weekly for 3 Weeks Every 28 Days in Patients with Advanced Solid Tumors

Clinical Cancer Research, September 2006
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Phase 1 Trial of the Antiangiogenic Peptide ATN-161 (Ac-PHSCN-NH2), a Beta Integrin Antagonist, in Patients with Solid Tumours

British Journal of Cancer, May 2006
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